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The Covid-19 Thread: News, Preparation Tips, Etc

lavaflow99

In search of the next vacation
Well.... :look:


Remdesivir Does Not Reduce COVID-19 Mortality, Study Says
Ralph Ellis
October 16, 2020





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Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center.
A large study sponsored by the World Health Organization found that remdesivir doesn't help hospitalized patients with COVID-19 survive and doesn't even shorten the recovery time of those who do survive.
These findings contradict smaller studies which found remdesivir, an antiviral drug, helped hospitalized coronavirus patients recover faster than patients who received a placebo. Those earlier studies led the FDA to grant emergency use authorization for the drug, which has been given to thousands of COVID patients in the United States, including President Donald Trump.
The WHO-sponsored study was conducted from March 22 to Oct. 4 and involved 11,330 patients from 405 hospitals in 30 countries. Patients were given remdesivir and three other drugs singly or in combination.

"These remdesivir, hydroxychloroquine, lopinavir and interferon regimens appeared to have little or no effect on hospitalized COVID-19, as indicated by overall mortality, initiation of ventilation and duration of hospital stay," the study concluded.
The data was posted online in the preprint server medRxiv and has not been peer-reviewed or published in a scientific journal.
U.S. pharmaceutical company Gilead Sciences, the maker of remdesivir, issued a statement defending the drug, noting that controlled studies published in peer-reviewed journals validated its benefits.
Gilead also questioned how the study was conducted, saying there was variation in "trial adoption, implementation, controls and patient populations and consequently, it is unclear if any conclusive findings can be drawn from the study results."

Dr. Peter Chin-Hong, MD, an infectious-disease expert at the University of California, San Francisco, told The New York Times that a massive study in different nations could result in inconsistent treatment methods.
"So much goes into care," he said. "The drug is only part of it."
Remdesivir was developed to treat Ebola and was repurposed to treat coronavirus. It has been one of the few encouraging developments in the global battle against COVID-19.
"It's certainly disappointing," Julie Fischer, an associate research professor in the Department of Microbiology and Immunology at Georgetown University, said of the study, according to Al Jazeera. "What all of us would like to see is what is frequently called a 'magic bullet'; a drug that's already in existence, that is safe and works effectively in patients. Unfortunately, in this case, this trial at least suggests the benefits of remdesivir weren't there at all."

The FDA granted emergency use authorization to remdesivir in April, saying: "While there is limited information known about the safety and effectiveness of using remdesivir to treat people in the hospital with COVID-19, the investigational drug was shown in a clinical trial to shorten the time to recovery in some patients."

A clinical trial of about 1,000 patients conducted by the National Institutes of Health found remdesivir shortened recovery time in about 31% of patients. The NIH also said the trial "suggested a survival benefit, with a mortality rate of 8.0% for the group receiving remdesivir versus 11.6% for the placebo group."

But the WHO-sponsored study said remdesivir and the other drugs just didn't work.

"The unpromising overall findings from the regimens tested suffice to refute early hopes, based on smaller or non-randomized studies, that any will substantially reduce inpatient mortality, initiation of ventilation or hospitalisation duration," the study said.

Sources:

MedRxiv. "Repurposed antiviral drugs for COVID-19; interim WHO SOLIDARITY trial results"

https://www.medrxiv.org/content/10.1101/2020.10.15.20209817v1

Gilead. "GILEAD SCIENCES STATEMENT ON THE SOLIDARITY TRIAL"


New York Times. "Remdesivir Fails to Prevent Covid-19 Deaths in Huge Trial"


Al Jazerra. "WHO trial finds remdesivir has little effect on COVID-19"


WebMD. "FDA Gives Remdesivir Emergency Authorization"

 

sunshinebeautiful

Well-Known Member
I mentioned a few months ago it would move from urban areas to rural central states and here we are. Those same governors aren't claiming its fake anymore. Especially since cities in the central states are running out of ICU beds. tRump keeps LYING about NY...saying everyone is dying there when in reality the infection rate is down to 1%. Here in North florida SURROUNDED by rural counties, our county still has a 7-8% infection rate. Not to mention the fact that the graveyard next to my job has been digging holes overtime. Doggone DeSantis doesn't care about us. Just businesses. The sad part is...many of these businesses might not make it past Christmas.
LAWD.... so scary. I live in South Florida, but my whole family is in Jacksonville. Totally know what you mean about the rural counties. Sheesh. I tell you what - I was driving up to see my parents a few months ago. On the Turnpike, I pass a big truck that had the name of a casket company on the side. This whole thing is totally and completely surreal.
 

awhyley

Well-Known Member
Kind of like :nono:

Not to mention the fact that the graveyard next to my job has been digging holes overtime.
:cry4: That's the saddest thing I've read in a while.

Listen, if this is how you need to get what you need to protect yourself, THEN SUCK IT UP & DO IT. This dudes only mistake was putting his face on the internets.

My prayer is that alot of people are "MAGA-ing" to get by and that the blue wave is actually a blue tsunami in November.
 

vevster

Well-Known Member
True but I thought people would get into it on their own. You can't get the drugs he was on unless you're sick and, even then, you can't get the experimental stuff. But vitamin d, zinc, and all the stuff we've discussed here is available to everyone. I guess I thought that it would be "legitimized" since the president's doctors have him on it but it seems it was just glossed over. I'm disappointed but I guess I shouldn't be surprised.
They are also talking about it as a treatment not preventative / mitigation.
 

vevster

Well-Known Member
I like these masks. 3 different styles, kids version, nice colors.

 

lavaflow99

In search of the next vacation

The disregard for life is astonishing especially when you consider their loved ones will be the first to fall ill.
When I first saw this, I thought it was a typo thinking how does anyone know 10,000 to attend one wedding? Had to be 1,000 (which is still crazy but more believable).

Then saw the population and understood this wasn't a typo. :nono: This religious group are full of entitled and irresponsible imbeciles. Can we put them in a bubble so that they don't interact with us rational people?
 

Ganjababy

Well-Known Member
My 18 year old niece started university a month ago. Moved away from home to university. They are not going to classes but are expected to stay in their dorms and study and take classes Online. She is a social butterfly and never been away from home for more than one night. Very close to her mom and siblings. COVID (2 close family members of hers had it and one was hospitalize) and isolation has been hard on her. Since it’s onset she has been diagnosed with anxiety and depression and a few other stuff.

In addition (my sis) her mom and Dad are going through a divorce (my BIL showed his true colours during COVID and sis had to file). Her house mate (they went to high school together) called her mom (my sis) and told her that she was fearing that my niece was going to kill herself so she had to hide all the knives in the dorm. Imagine our shock. This kid is the most happy go lucky girl you could find. Bright (accepted to all the universities she applied to). Beautiful and popular and happy before this. She has been admitted to a psych ward. :cry3: :cry3: :cry3: :cry3: :cry3: :cry3: :cry3: She asked her mom not tell tell anyone in the family because she is sooo embarrassed:cry3:I gave her mom permission to talk to her about my own struggles with mental health (the kids in my family were not told or exposed to it) in the hopes that it would lessen her shame. My poor sister is going through it...
 
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sunshinebeautiful

Well-Known Member
My 18 year old niece started university a month ago. Moved away from home to university. They are not going to classes but are expected to stay in their dorms and study and take classes Online. She is a social butterfly and never been away from home for more than one night. Very close to her mom and siblings. COVID (2 close family members of hers had it and one was hospitalize) and isolation has been hard on her. Since it’s onset she has been diagnosed with anxiety and depression and a few other stuff.

In addition (my sis) her mom and Dad are going through a divorce (my BIL showed his true colours during COVID and sis had to file). Her house mate (they went to high school together) called her mom (my sis) and told her that she was fearing that my niece was going to kill herself so she had to hide all the knives in the dorm. Imagine our shock. This kid is the most happy go lucky girl you could find. Bright (accepted to all the universities she applied to). Beautiful and popular and happy before this. She has been admitted to a psych ward. :cry3: :cry3: :cry3: :cry3: :cry3: :cry3: :cry3: She asked her mom not tell tell anyone in the family because she is sooo embarrassed:cry3:I gave her mom permission to talk to her about my own struggles with mental health (the kids in my family were not told or exposed to it) in the hopes that it would lessen her shame. My poor sister is going through it...
OMG. I am so sorry to hear about your niece. This entire thing - with no end in sight - has been taking its psychological and emotional toll on people left and right. A lot college freshmen suffer from homesickness in a regular school year after moving away from home - so to leave home, go off to college, and have to sit in a dorm room and isolate and take classes online *has* to be a whole lot.
 

vevster

Well-Known Member
I spoke to a white friend over the weekend. She says she doesn't know of anyone that caught covid. I don't think I know any black person with that status. She lives in Red Hook, Brooklyn.
 

Maracujá

November 2020 --> 14 years natural!!!
I spoke to a white friend over the weekend. She says she doesn't know of anyone that caught covid. I don't think I know any black person with that status. She lives in Red Hook, Brooklyn.
Do you mean that most Black people you know, did catch COVID-19? Esp. those living in that area?
 

vevster

Well-Known Member
The orthodox jews in NY are crying racism. I saw this guy call a girl a racist because her business was full and she couldn't let him in.
 

Shimmie

"God is the Only Truth -- Period"
Staff member
My 18 year old niece started university a month ago. Moved away from home to university. They are not going to classes but are expected to stay in their dorms and study and take classes Online. She is a social butterfly and never been away from home for more than one night. Very close to her mom and siblings. COVID (2 close family members of hers had it and one was hospitalize) and isolation has been hard on her. Since it’s onset she has been diagnosed with anxiety and depression and a few other stuff.

In addition (my sis) her mom and Dad are going through a divorce (my BIL showed his true colours during COVID and sis had to file). Her house mate (they went to high school together) called her mom (my sis) and told her that she was fearing that my niece was going to kill herself so she had to hide all the knives in the dorm. Imagine our shock. This kid is the most happy go lucky girl you could find. Bright (accepted to all the universities she applied to). Beautiful and popular and happy before this. She has been admitted to a psych ward. :cry3: :cry3: :cry3: :cry3: :cry3: :cry3: :cry3: She asked her mom not tell tell anyone in the family because she is sooo embarrassed:cry3:I gave her mom permission to talk to her about my own struggles with mental health (the kids in my family were not told or exposed to it) in the hopes that it would lessen her shame. My poor sister is going through it...
:pray: I’m so sorry about your niece and her struggles. I’m praying for your family. God’s love will heal and bring your family through this. Your niece will be comforted and healed.

I pray for all in this forum to have God’s peace and healing. So much is going on all at once; it’s a very stressful time for all. Please be encouraged. :pray:
 

meka72

Well-Known Member
I really want to urge everyone to buy an oximeter and to encourage their loved ones to do so as well. In addition to my mother and step father, my sister, her husband and MIL all tested c19 positive. Luckily my sister bought all the things that I bought my parents including an oximeter because he was able to make it to the ER when his oxygen went down to 82. He’s been in the hospital for 3 days at this point and the doctors are weaning him off oxygen.

His mother first tested c19 negative before testing positive a few days later. They are in the same hospital.

My stepfather, whose at home, and my sister’s husband are both being treated for covid pneumonia.
 

Reinventing21

Spreading my wings
At first I thought that this would only be great for children, but on re-watch, it's better for adults. The messaging is excellent.

I don't know if you watched the whole video, but it is definitely a video for adults, not kids (especially younger kids). Very clever video. I think they used a kid cartoon to make it more relatable to the general mentality of those who refuse to wear masks.
 

Everything Zen

Well-Known Member
I don’t even know where to put this but my eyesight has deteriorated due to steroids from my annual bout of bronchitis that I have to have cataract surgery on both eyes before the end of the year or lose my license. It’s gonna be complicated and super expensive with the out of pocket costs bc I’m like one of the youngest ophthalmology patients at 38 so I can’t just get the standard geriatric lens. I just had laser eye surgery last year in December bc I also had elevated IOP and am considered pre-glaucoma. My dad lost a ton of vision in his left eye earlier this year bc he has a severe case but he’s 76. At this point I’m just drinking hot toddy’s and cracking up at all this mess in 2020 bc what else are you gonna do? :lol:
 

sunshinebeautiful

Well-Known Member
I don’t even know where to put this but my eyesight has deteriorated due to steroids from my annual bout of bronchitis that I have to have cataract surgery on both eyes before the end of the year or lose my license. It’s gonna be complicated and super expensive with the out of pocket costs bc I’m like one of the youngest ophthalmology patients at 38 so I can’t just get the standard geriatric lens. I just had laser eye surgery last year in December bc I also had elevated IOP and am considered pre-glaucoma. My dad lost a ton of vision in his left eye earlier this year bc he has a severe case but he’s 76. At this point I’m just drinking hot toddy’s and cracking up at all this mess in 2020 bc what else are you gonna do? :lol:
Girl. Good luck with your surgery. I also think you're the youngest person I know who's needed one. My mom has to get hers done soon.
 

Everything Zen

Well-Known Member
Girl. Good luck with your surgery. I also think you're the youngest person I know who's needed one. My mom has to get hers done soon.
I wish your mom the best as well. I didn’t even know it was that bad bc my eyesight has sucked for the past year. I was like hey not bad! I did pretty good! They couldn’t even find my optic nerve in the machine bc the big cataract was in the way. What are you gonna do? I’m just making light of it. I’m grateful to have a really good job with unlimited PTO and a boss that truly cares about us and our health comes first. People asking me to do stuff at work- no :censored: I’m blind! :lol:
 

Black Ambrosia

Well-Known Member
@Everything Zen Girl, you have more than my thoughts and prayers. I'm sending you my energy too. Sometimes all you can do is laugh about it. Or get a few drinks. Or both. I won't judge. I'll probably join you virtually.

Just when you think you've adjusted to 2020 it manages to surprise you.

My aunt passed last week. She hadn't been tested and the EMS determined it was natural causes but we don't know. Her symptoms could've been covid or something else. I tried to take her to urgent care the night she died but she refused and told me she'd go the day after. But the day after we found her in her home.

Found out over the weekend that a cousin has a brain tumor. It hasn't been confirmed yet but the assumption is that it's cancerous.

And this is random but my dentist is basically stalking me about my overdue dental cleaning. I appreciate the effort and concern about my health but I'm really not comfortable when I can't wear a mask and other people's germs, spittle, and whatever else is aerosolized in that space. Does anyone know what precautions dentists are taking? Maybe if they can assure me they're doing something special I'll consider going but I feel like I need to get my vitamin d levels tested before even thinking about it. I'm around my mother often and I'm not gonna do anything that indirectly puts her at risk.
 

Black Ambrosia

Well-Known Member
I mean that all black people that I KNOW have either caught Covid and or have friends & fam that have caught it.
I know you are in Europe, so it may be different for you.
I think it's still regional tbh. I'm in Detroit. You're in New York. Both areas were hit hard really early. I know of 4 people in a one block radius here but I have friends in Atlanta who haven't been touched by it at all. One friend was telling me in May how nothing was shut down and life wasn't any different aside from her job making everyone work at home. And she was complaining because she's doing more work from home than she would in the office. I can relate but it still bothered me because I could tell she didn't get how serious it is. Ironically she got covid in August and still isn't sure how but thinks it was a relative who had an inconclusive test result.
 
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